Author: O. Fadriyanti, W. Widyawati and B. A. Gani

DOI: http://doi.org/10.31788/RJC.2023.1638158

This study evaluated the potential of Ziziphus mauritiana Lam (Z. mauritiana Lam) ethanol extract improves thermal stability and strength to prevent the growth and biofilm formation of C. albicans.The assessment of heat release (thermal equilibrium) of acrylic resin using Differential scanning calorimetry, the strength of acrylic resin with the universal testing machine, growth assessment of C. albicans by spectrophotometry, and biofilm assay with crystal violet and visual images used to a microscope. Z. mauritiana Lam 12.5% provides better thermal stability with a cooling peak enthalpy of -223.27 cal/g. In addition, concentrations of 6.25% and 3.125% at 48 hours had a better ability to increase the strength of acrylic resin (p>0.05). Z. mauritiana Lam at all concentrations and incubation of 24 and 48 hours were similar in decreasing the growth of C. albicans (0.06-0.08 or equivalent to <300 cfu="">0.05). The Z. mauritiana Lam increased heat release (thermal stability) in acrylic resin, which caused an increase in transverse strength. At the same time, it reduces the growth and biofilm formation of C. albicans on the acrylic resin surface.

Keywords: Biofilm, Candida albicans, Growth, Denture stomatitis, Ziziphus mauritiana Lam.