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SYNTHESIS, CHARACTERIZATION, AND MULTIFUNCTIONAL APPLICATIONS OF 2-NITROHYDRAZIDE AND 4-NITRO HYDRAZIDE STABILIZEDSILVER NANOPARTICLES FOR CATALYTIC DYE DEGRADATION, METAL ION DETECTION, ANTICANCER, AND ANTIMICROBIAL ACTIVITIES


Author: Y. Desai, T. Barot,S. Patel, N. Pomal, D. Patni, P. Patel and H. Kardani
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Abstract

Silver nanoparticles were produced by a chemical reduction process, wherein Ag + ions from AgNO3 were convertedto metallic Ag 0 utilising an appropriate reducing agent such as hydrazine. By acting as a stabilising and cappingagent, the synthesised hydrazine-based ligand maintained the stability of the nanoparticles and preventedagglomeration. The synthesis of 2-nitrohydrazide-capped silver nanoparticles (2-NHAgNPs) was carried out usingthe conventional method, while the synthesis of 4-nitrohydrazide-capped silver nanoparticles (4-NHAgNPs) wasperformed using the ultrasonic method. Silver nanoparticles were synthesised via a typical one-pot chemical reduction method. Comprehensive characterisation using UV-Visible Spectroscopy, Fourier TransformInfraredSpectroscopy, Transmission Electron Microscopy, Particle size distribution, and zeta potential confirmedthesuccessful formation of 2-NHAgNPs and 4-NHAgNPs. Furthermore, the 2-NHAgNPs and 4-NHAgNPs exhibit remarkable anticancer effects against the human Brest cancer cell line MCF-7, different dye degradation, varioussensing of metal ions and gram-positive and gram- negative antimicrobial activity.

Keywords: Silver Nanoparticles, Anti-cancer, 2-NHAgNPs, 4-NHAgNPs






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