ISOLATION AND CHARACTERIZATION OF TWO NOVEL DEGRADANT PRODUCTS IN ITRACONAZOLE BY USING PREPâ€‘HPLC, HRMS AND NMR

Santhosh Guduru; V.V.S.R.N. Anji Karun Mutha; Muralidharan Kaliyaperumal; Chidananda Swamy Rumalla; Raghu Babu Korupolu and Kishore Babu Bonige

doi:10.31788/RJC.2019.1215077

ISOLATION AND CHARACTERIZATION OF TWO NOVEL DEGRADANT PRODUCTS IN ITRACONAZOLE BY USING PREPâ€‘HPLC, HRMS AND NMR

Author: Santhosh Guduru, V.V.S.R.N. Anji Karun Mutha, Muralidharan Kaliyaperumal, Chidananda Swamy Rumalla, Raghu Babu Korupolu and Kishore Babu Bonige

DOI: http://dx.doi.org/10.31788/RJC.2019.1215077

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Abstract

Keywords: Itraconazole, prep-HPLC, Impurities, Mass Spectrometry, NMR, Isolation and characterization.

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